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In most cases, yes if it's caught and corrected

Pustular dermatoses were not the most frequent eruption occurring after vaccination An increasing number of studies are providing additional information regarding the immunological response of COVID-19 vaccines and attempting to elucidate the development of post-vaccine skin manifestations, including pustular eruptions

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15 Previously, questions have been raised about whether the observed pharmacological activity in humans following kratom administration is due to mitragynine or mediated by the metabolite, 7-HMG